With the coming of the railroad in the 1860s, Buffalo County would continue to develop. One of the stations that sprang up was Kearney, the county seat. Originally named Fort Childs, it was later renamed Kearney Junction and finally shortened to Kearney. Moses H. Sydenham, one of the early pioneers in the county, founded a newspaper in this young settlement and used the publication to promote his idea that Kearney, with its central location, should become the capital of the United States.
Hardships such as hot, dry weather and severe blizzards were not uncommon for the early residents of the county. But the most serious challenge faced by those who worked the land was the damage done by waves of grasshoppers that swarmed over the area in the mid 1870s.
More than 115 years later, Buffalo County is a thriving agricultural and industrial area. It also pays an important role in the state's higher education system, with the University of Nebraska at Kearney located in the county seat.